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New study shows Alzheimer’s disease can be reversed to full neurological recovery—not just prevented or slowed—in animal models. Using mouse models and human brains, study shows brain’s failure to maintain cellular energy molecule, NAD+, drives AD, and maintaining NAD+ prevents or even reverses it. • Dec 25, 2025 at 6:10 AM • case.edu • r/science
619
Mattermost restricted access to old messages after 10000 limit is reached • Dec 25, 2025 at 6:03 AM • github.com/mattermost • Hacker News
1431
We invited a man into our home at Christmas and he stayed with us for 45 years • Dec 25, 2025 at 5:35 AM • bbc.co.uk • Hacker News
71
Gleam v1.14 - the happy holidays release 2025 • Dec 25, 2025 at 2:42 AM • gleam.run • Lobsters
35
exe.dev, a service for creating Linux virtual machines and vibe-coding in them • Dec 25, 2025 at 12:46 AM • exe.dev • ~comp
261
Free Software Foundation receives historic private donations • Dec 24, 2025 at 11:47 PM • fsf.org • Hacker News
940
Ruby 4.0.0 • Dec 24, 2025 at 11:13 PM • ruby-lang.org • Hacker News
75
Ruby 4.0.0 Released • Dec 24, 2025 at 10:50 PM • ruby-lang.org • Lobsters
34
First finished hand-embroidered patch. *Very* late Timasomo entry... • Dec 24, 2025 at 10:10 PM • tildes.net • ~creative
84
Pope Leo, on Christmas Eve, says denying help to poor is rejecting God • Dec 24, 2025 at 9:25 PM • reuters.com • ~humanities
15
Mathematically extra-complicated Secretest Santa 2025 • Dec 24, 2025 at 9:25 PM • youtube.com • ~tech
31
Turtle WoW's remake of World of Warcraft using Unreal Engine is reportedly cancelled • Dec 24, 2025 at 8:56 PM • pcgamesn.com • ~games
139
'Why I Quit Streaming And Got Back Into Cassettes' • Dec 24, 2025 at 8:25 PM • 404media.co • Slashdot
212
Package managers keep using git as a database, it never works out • Dec 24, 2025 at 7:49 PM • nesbitt.io • Lobsters
415
Who Watches the Waymos? I do [video] • Dec 24, 2025 at 7:10 PM • youtube.com • Hacker News
393
Microsoft please get your tab to autocomplete shit together • Dec 24, 2025 at 6:33 PM • ivanca.github.io • Hacker News
315
Asterisk AI Voice Agent • Dec 24, 2025 at 6:25 PM • github.com/hkjarral • Hacker News
2385
Tell HN: Merry Christmas • Dec 24, 2025 at 5:56 PM • news.ycombinator.com • Hacker News
1076
Phoenix: A modern X server written from scratch in Zig • Dec 24, 2025 at 5:43 PM • git.dec05eba.com • Hacker News
531
How I Left YouTube • Dec 24, 2025 at 4:54 PM • zhach.news • Hacker News
1086
Nvidia to buy assets from Groq for $20B cash • Dec 24, 2025 at 4:02 PM • cnbc.com • Hacker News
632
Show HN: Minimalist editor that lives in browser, stores everything in the URL • Dec 24, 2025 at 2:42 PM • github.com/antonmedv • Hacker News
43P
Russia Plans a Nuclear Power Plant on the Moon Within a Decade • Dec 24, 2025 at 2:01 PM • reuters.com • science.slashdot
482
Fabrice Bellard: Biography (2009) [pdf] • Dec 24, 2025 at 1:17 PM • ipaidia.gr • Hacker News
100P
Some of DOJ's Careful Redactions Can Be Defeated With Copy-Paste • Dec 24, 2025 at 1:01 PM • theverge.com • Slashdot
16
What have you been watching / reading this week? (Anime/Manga) • Dec 24, 2025 at 1:00 PM • tildes.net • ~anime
560
Show HN: Vibium – Browser automation for AI and humans, by Selenium's creator • Dec 24, 2025 at 12:49 PM • github.com/VibiumDev • Hacker News
499
Zelda: Twilight Princess Has Been Decompiled • Dec 24, 2025 at 12:36 PM • timeextension.com • r/programming
22
Do we really need all these long-duration energy storage (LDES) technologies to hit the net-zero target? • Dec 24, 2025 at 12:07 PM • youtube.com • ~enviro
13
NASA will soon find out if the Perseverance rover can really persevere on Mars • Dec 24, 2025 at 11:58 AM • arstechnica.com • ~space
284
Frontend decisions are harder to justify on the spot than backend ones • Dec 24, 2025 at 11:32 AM • reddit.com • r/webdev
6657
Neanderthals may have been "absorbed" rather than extinguished: A simple analytical model shows constant gene flow from larger Homo sapiens populations could explain the Neanderthal disappearance within 30,000 years. • Dec 24, 2025 at 10:49 AM • nature.com • r/science
379
Why We Abandoned Matrix (2024) • Dec 24, 2025 at 10:06 AM • forum.hackliberty.org • Hacker News
290
AMD entered the CPU market with reverse-engineered Intel 8080 clone 50 years ago • Dec 24, 2025 at 9:28 AM • tomshardware.com • Hacker News
343
When compilers surprise you • Dec 24, 2025 at 8:27 AM • xania.org • Hacker News
259
How do you create this effect? • Dec 24, 2025 at 8:17 AM • reddit.com • r/webdev
129
I'm returning my Framework 16 • Dec 24, 2025 at 8:03 AM • yorickpeterse.com • Lobsters
169P
US Bars Five Europeans It Says Pressured Tech Firms To Censor American Viewpoints Online • Dec 24, 2025 at 8:00 AM • apnews.com • yro.slashdot
888
I'm returning my Framework 16 • Dec 24, 2025 at 7:55 AM • yorickpeterse.com • Hacker News
70
I love X, and I love Grok • Dec 24, 2025 at 7:52 AM • phong.bearblog.dev • Bear